Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12957245 | 0.94 | PSMB5 (0.49) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL10205844 | 0.90 | PSMB5 (0.51) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL18606213 | 0.88 | PSMB5 (0.50) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL24066439 | 0.79 | NPC1 (0.46) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL18136475 | 0.79 | PSMB5 (0.53) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL14478722 | 0.78 | MAP4K4 (0.50) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL17805945 | 0.77 | RAB9A (0.54) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A | |
| SCHEMBL15785404 | 0.76 | MAP4K4 (0.71) | PSMB5SMN1; SMN2RAB9ANPC1MAP4K4 | |
| SCHEMBL29361094 | 0.76 | MAP4K4 (0.71) | PSMB5SMN1; SMN2RAB9ANPC1MAP4K4 | |
| SCHEMBL13141949 | 0.76 | PSMB5 (0.50) | PSMB5PDGFRBPDGFRASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275409-A1 | Bipiridine derivative and organic electroluminescence element containing the same | Yamagata Promotional Organization for Industrial Technology (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20100327265-A1 | BIPIRIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING THE SAME | YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100327265-A1 | BIPIRIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING THE SAME | YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327265-A1 | BIPIRIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING THE SAME | NFE2L2, SLC19A2, AOC2 | PSMB5 2825/4885PDGFRB 2247/4885PDGFRA 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.