Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616801 | 0.93 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL17055533 | 0.91 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL17055529 | 0.84 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL19037254 | 0.84 | L3MBTL1 (0.47) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL17055440 | 0.82 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL12786339 | 0.80 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL29457649 | 0.79 | CYP2A6 (0.58) | RAB9ANPC1L3MBTL1ALDH1A1PDGFRB | |
| SCHEMBL21808799 | 0.79 | CYP2A6 (0.58) | RAB9ANPC1L3MBTL1ALDH1A1PDGFRB | |
| SCHEMBL23253726 | 0.78 | PSMB5 (0.33) | PSMB5PDGFRBPDGFRA | |
| SCHEMBL10021910 | 0.77 | NPC1 (0.35) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3935129-B1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2023-11-29 | — | — | EP | disclosed |
| US-11778907-B2 | Composition for organic electronic devices | MERCK PATENT GMBH (DE) | 2023-10-03 | — | — | US | disclosed |
| EP-3237387-B1 | HETEROCYCLIC COMPOUNDS WITH DIBENZAZAPINE STRCTURES | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | US | disclosed |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
| EP-3712229-A1 | MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2020-09-23 | — | — | EP | disclosed |
| US-10777750-B2 | Heterocyclic spiro compounds | BASF SE (DE) | 2020-09-15 | — | — | US | disclosed |
| EP-3027708-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, LEF1, KCNC1 | RAB9A 1310/4885NPC1 2156/4885SMN1; SMN2 2008/4885 |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | RAB9A 1935/4885NPC1 2116/4885SMN1; SMN2 3900/4885 |
| US-20160181548-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPHB3, EPHA3, EPHB4 | RAB9A 1107/4885NPC1 4210/4885SMN1; SMN2 3265/4885 |
| US-20230210004-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPHB3, EPHA3, EPHB4 | RAB9A 1107/4885NPC1 4210/4885SMN1; SMN2 3265/4885 |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | RAB9A 1935/4885NPC1 2116/4885SMN1; SMN2 3900/4885 |
| US-10777750-B2 | Heterocyclic spiro compounds | NES, KCNC1, HCN4 | RAB9A 1935/4885NPC1 2116/4885SMN1; SMN2 3900/4885 |
| US-20160164002-A1 | MATERIALS FOR ELECTRONIC DEVICES | EPX, EFNA1, GPX4 | RAB9A 2571/4885NPC1 4834/4885SMN1; SMN2 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.