SCHEMBL129591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2538579	0.83	ACHE (0.43)	CYP1A2CYP2C19HTR2AHTR2CHTR2B
	SCHEMBL548707	0.83	CYP1A2 (0.42)	CYP1A2CYP2C19CYP4F2CYP4A11LMNA
	SCHEMBL18802729	0.83	TAAR1 (0.46)	CYP1A2CYP2C19CYP4F2CYP4A11CETP
	SCHEMBL129592	0.83	KIF11 (0.46)	CYP1A2CYP2C19CYP4F2CYP4A11CETP
	SCHEMBL2636462	0.82	PDK1 (0.44)	CYP1A2CYP2C19CYP4F2CYP4A11LMNA
	SCHEMBL23501574	0.80	CYP1A2 (0.44)	CYP1A2CYP2C19CYP4F2CYP4A11LMNA
	SCHEMBL13316137	0.80	CYP4F2 (0.42)	CYP1A2CYP2C19CYP4F2CYP4A11LMNA
	SCHEMBL18802813	0.80	TAAR1 (0.43)	CYP1A2CYP2C19CYP4F2CYP4A11CETP
	SCHEMBL1908518	0.80	ENPP2 (0.50)	CYP1A2CYP2C19CYP4F2CYP4A11HTR2A
	SCHEMBL7158092	0.80	CETP (0.40)	CYP1A2CYP2C19CYP4F2CYP4A11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.