Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.58 |
| ▸ | PPARD | Q03181 | 15/20 | 0.58 |
| ▸ | PPARG | P37231 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966539 | 0.85 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL12966532 | 0.83 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL12966538 | 0.82 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL11566625 | 0.78 | PPARG (0.70) | PPARAPPARDPPARG | |
| SCHEMBL12966540 | 0.76 | LTA4H (0.60) | — | |
| SCHEMBL12966537 | 0.76 | CYP1A2 (0.46) | PPARAPPARG | |
| SCHEMBL2475726 | 0.76 | LMNA (0.50) | — | |
| SCHEMBL4036197 | 0.76 | PPARG (0.66) | PPARAPPARDPPARG | |
| SCHEMBL3811479 | 0.76 | PPARA (0.81) | PPARAPPARDPPARG | |
| SCHEMBL17991985 | 0.74 | LMNA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |