Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966547 | 0.93 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNALTA4HKDM4E | |
| SCHEMBL12966654 | 0.86 | GAA (0.54) | ALDH1A1L3MBTL1LMNALTA4HKDM4E | |
| SCHEMBL12966540 | 0.85 | LTA4H (0.60) | L3MBTL1LMNALTA4HNPC1MAPT | |
| SCHEMBL38663 | 0.85 | PPARA (0.51) | L3MBTL1LMNALTA4HNPC1MAPT | |
| SCHEMBL43048 | 0.85 | PPARA (0.51) | L3MBTL1LMNALTA4HNPC1MAPT | |
| SCHEMBL12966531 | 0.84 | L3MBTL1 (0.47) | L3MBTL1LMNALTA4HKDM4ENPC1 | |
| SCHEMBL12966899 | 0.82 | GAA (0.52) | ALDH1A1L3MBTL1LMNALTA4HKDM4E | |
| SCHEMBL12966546 | 0.79 | PPARA (0.57) | L3MBTL1LMNALTA4HNPC1MAPT | |
| SCHEMBL12966674 | 0.78 | PPARA (0.63) | L3MBTL1LTA4HNPC1MAPTRAB9A | |
| SCHEMBL2475367 | 0.78 | LMNA (0.72) | ALDH1A1LMNAKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |