Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966543 | 0.87 | NPC1 (0.42) | MAPTNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL12966650 | 0.84 | MAPT (0.60) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL12966653 | 0.78 | MAPT (0.55) | MAPTNPC1RAB9ATSHRL3MBTL1 | |
| SCHEMBL12966622 | 0.75 | NPC1 (0.44) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12966900 | 0.74 | MAPT (0.59) | MAPTNPC1RAB9ATSHRTDP1 | |
| SCHEMBL12966623 | 0.73 | NPC1 (0.42) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL12966897 | 0.73 | MAPT (0.53) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL12966652 | 0.71 | MAPT (0.51) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL47175 | 0.70 | MAPT (0.62) | MAPTNPC1RAB9ATSHRL3MBTL1 | |
| SCHEMBL12966626 | 0.69 | MAPT (0.48) | MAPTNPC1RAB9AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |