Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 1.00 |
| ▸ | F3 | P13726 | 4/20 | 1.00 |
| ▸ | USP7 | Q93009 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.79 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.79 |
| ▸ | CES1 | P23141 | 3/20 | 0.79 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.79 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.79 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.79 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.79 |
| ▸ | PTPRC | P08575 | 2/20 | 0.79 |
| ▸ | PTPRF | P10586 | 2/20 | 0.79 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.79 |
| ▸ | ACP1 | P24666 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hederagenin SCHEMBL18818579 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL359809 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL13395362 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL29523111 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL15382983 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL18704478 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL12919815 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL18293409 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL21892153 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA | |
| Hederagenin SCHEMBL14132125 | 1.00 | PTPN1 (1.00) | PTPN1F3USP7USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290536-B2 | C4 monomethyl triterpenoid derivatives and methods of use thereof | REATA PHARMACEUTICALS, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20120252776-A1 | C4 Monomethyl Triterpenoid Derivatives and Methods of Use Thereof | REATA PHARMACEUTICALS, INC. | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252776-A1 | C4 Monomethyl Triterpenoid Derivatives and Methods of Use Thereof | CYP4A11, LTC4S, NOX4 | PTPN1 3346/4885F3 77/4885USP7 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.