Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | PDE8A | O60658 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | PDE6A | P16499 | 1/20 | 0.39 |
| ▸ | PDE6G | P18545 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE6B | P35913 | 1/20 | 0.39 |
| ▸ | PDE6C | P51160 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12850767 | 0.85 | MAPT (0.43) | BRAFPDE10APDE2APDE6DPDE8A | |
| SCHEMBL20893121 | 0.85 | ADORA2A (0.47) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL16021113 | 0.81 | ADORA3 (0.49) | GABRPGABRDADORA3GABRA1GABRB1 | |
| SCHEMBL9416616 | 0.72 | POLB (0.44) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL29033149 | 0.71 | PDE2A (0.41) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL20893214 | 0.70 | KDM4E (0.44) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL9416648 | 0.70 | ADORA3 (0.44) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL9261073 | 0.69 | KMT2A (0.45) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL9264212 | 0.69 | ADORA3 (0.41) | PDE10APDE2APDE6DPDE8APDE5A | |
| SCHEMBL9264131 | 0.69 | KMT2A (0.47) | POLBMEN1KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130709-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2012-10-04 | — | — | WO | disclosed |