Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416648 | 0.87 | ADORA3 (0.44) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL9264131 | 0.81 | KMT2A (0.47) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL9260636 | 0.76 | KDM4E (0.39) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL9416616 | 0.76 | POLB (0.44) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL9264212 | 0.73 | ADORA3 (0.41) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL9261860 | 0.70 | POLB (0.48) | KMT2AMEN1POLBALDH1A1RAB9A | |
| SCHEMBL9416659 | 0.69 | KDM4E (0.38) | KMT2AMEN1POLBADORA3GABRA2 | |
| Hydrochloric Acid SCHEMBL9263011 | 0.68 | KDM4E (0.37) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL12850767 | 0.67 | MAPT (0.43) | KMT2AMEN1POLBADORA3GABRA2 | |
| SCHEMBL9262552 | 0.67 | NR4A2 (0.45) | KMT2AMEN1POLBGABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |