Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264212 | 0.87 | ADORA3 (0.41) | POLBLMNAADORA3GABRPGABRD | |
| SCHEMBL9264131 | 0.86 | KMT2A (0.47) | POLBADORA3GABRPGABRDGABRA1 | |
| SCHEMBL9261860 | 0.81 | POLB (0.48) | POLBLMNAKDM4EMEN1KMT2A | |
| SCHEMBL9262552 | 0.81 | NR4A2 (0.45) | POLBLMNAGABRA1GABRB1GABRG2 | |
| SCHEMBL9416648 | 0.79 | ADORA3 (0.44) | POLBADORA3GABRPGABRDGABRA1 | |
| SCHEMBL9261373 | 0.77 | LMNA (0.47) | POLBLMNAADORA1KDM4EMEN1 | |
| SCHEMBL9261073 | 0.76 | KMT2A (0.45) | POLBADORA3GABRPGABRDGABRA1 | |
| SCHEMBL9256941 | 0.75 | LMNA (0.46) | POLBLMNAGABRA1GABRB1GABRG2 | |
| SCHEMBL20893121 | 0.74 | ADORA2A (0.47) | POLBLMNAADORA3GABRPGABRD | |
| SCHEMBL16416864 | 0.73 | MAPT (0.50) | POLBLMNAGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |