Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416616 | 0.86 | POLB (0.44) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL9264212 | 0.83 | ADORA3 (0.41) | KMT2AMEN1POLBHSD17B10ALDH1A1 | |
| SCHEMBL9261073 | 0.81 | KMT2A (0.45) | KMT2AMEN1POLBHSD17B10ALDH1A1 | |
| SCHEMBL9261860 | 0.80 | POLB (0.48) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL9262552 | 0.77 | NR4A2 (0.45) | KMT2AMEN1POLBHSD17B10KDM4E | |
| SCHEMBL9416648 | 0.73 | ADORA3 (0.44) | KMT2AMEN1POLBHSD17B10ALDH1A1 | |
| SCHEMBL27500927 | 0.70 | GABRA1 (0.72) | HSD17B10SLC2A2KDM4EADORA3GABRA1 | |
| SCHEMBL12850767 | 0.69 | MAPT (0.43) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL20893121 | 0.68 | ADORA2A (0.47) | KMT2AMEN1POLBHSD17B10ALDH1A1 | |
| SCHEMBL27589977 | 0.68 | SLC2A2 (0.50) | KMT2AMEN1POLBHSD17B10SLC2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |