Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12975770 | 1.00 | CNR1 (0.49) | CNR1MMP1MMP2MMP3KCNK3 | |
| SCHEMBL12975638 | 1.00 | CNR1 (0.49) | CNR1MMP1MMP2MMP3KCNK3 | |
| SCHEMBL9966033 | 0.86 | MMP1 (0.50) | MMP1MMP2MMP3ALDH1A1HSD17B10 | |
| SCHEMBL8224748 | 0.86 | MMP1 (0.50) | MMP1MMP2MMP3ALDH1A1HSD17B10 | |
| SCHEMBL12975411 | 0.82 | CYP3A4 (0.47) | CNR1MMP1MMP2TDP1HSD17B10 | |
| SCHEMBL23176110 | 0.80 | ALDH1A1 (0.43) | CNR1MMP1MMP2MMP3ALDH1A1 | |
| SCHEMBL13097700 | 0.80 | CYP3A4 (0.46) | CNR1MMP1MMP2TDP1HSD17B10 | |
| SCHEMBL26709641 | 0.80 | CYP3A4 (0.46) | CNR1MMP1MMP2TDP1HSD17B10 | |
| SCHEMBL22304123 | 0.79 | CNR1 (0.63) | CNR1KCNK3ALDH1A1THRBCNR2 | |
| SCHEMBL14350673 | 0.78 | PAX8 (0.39) | CNR1HSD17B10CYP3A4MAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141330-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-09 | — | — | WO | disclosed |