SCHEMBL8224748

SCHEMBL8224748

CCC(C)NC(=O)C(C)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP3 P08254 1/20 0.50
PKM P14618 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 2/20 0.41
EPHX1 P07099 1/20 0.41
MEN1 O00255 1/20 0.41
RAB9A P51151 3/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9966033 1.00 MMP1 (0.50) MMP1MMP2MMP3PKMSMN1; SMN2
SCHEMBL12975643 0.86 CNR1 (0.49) MMP1MMP2MMP3PKMSMN1; SMN2
SCHEMBL12975638 0.86 CNR1 (0.49) MMP1MMP2MMP3PKMSMN1; SMN2
SCHEMBL12975770 0.86 CNR1 (0.49) MMP1MMP2MMP3PKMSMN1; SMN2
SCHEMBL23176110 0.84 ALDH1A1 (0.43) MMP1MMP2MMP3SMN1; SMN2ALDH1A1
SCHEMBL9462858 0.84 MMP1 (0.45) MMP1MMP2MMP3PKMSMN1; SMN2
SCHEMBL11527770 0.82 MMP1 (0.52) MMP1MMP2MMP3PKMSMN1; SMN2
SCHEMBL10031629 0.82 ALDH1A1 (0.42) MMP1MMP2CA12CA1CA2
SCHEMBL13876693 0.82 ALDH1A1 (0.42) MMP1MMP2CA12CA1CA2
SCHEMBL19699515 0.82 MMP1 (0.52) MMP1MMP2MMP3PKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180185263-A1 CLEAR SUSPENDING PERSONAL CARE CLEANSING COMPOSITIONS KENVUE BRANDS LLC 2018-07-05 US disclosed
US-9938243-B2 Compounds for affinity chromatography and for extending the half-life of a therapeutic agent GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2018-04-10 US disclosed
US-9937118-B2 Clear suspending personal care cleansing compositions JOHNSON & JOHNSON CONSUMER INC. (US) 2018-04-10 US disclosed
US-20170360680-A1 CLEAR SUSPENDING PERSONAL CARE CLEANSING COMPOSITIONS KENVUE BRANDS LLC 2017-12-21 US disclosed
US-9809558-B2 Compounds for affinity chromatography and for extending the half-life of a therapeutic agent GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-11-07 US disclosed
US-20170079893-A1 PHASE-STABLE SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS JOHNSON & JOHNSON CONSUMER INC. 2017-03-23 US disclosed
US-20170079892-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC. 2017-03-23 US disclosed
US-20160096904-A1 SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME AKZO NOBEL CHEMICALS INT BV (NL) 2016-04-07 US disclosed
US-9243074-B2 Superhydrophilic amphiphilic copolymers and processes for making the same AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-01-26 US disclosed
US-9114154-B2 Compositions comprising superhydrophilic amphiphilic copolymers and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. (US) 2015-08-25 US disclosed
US-20110082290-A1 SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-04-07 US disclosed
US-20110081310-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2011-04-07 US disclosed
US-20110081309-A1 COMPOSITIONS COMPRISING A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER AND A MICELLAR THICKENER KENVUE BRANDS LLC 2011-04-07 US disclosed
US-20110082105-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF KENVUE BRANDS LLC 2011-04-07 US disclosed
US-7714114-B2 Conjugates of an EPO moiety and a polymer NEKTAR THERAPEUTICS (US) 2010-05-11 US disclosed
EP-1954698-B1 SPIROCYCLIC COMPOUNDS AS HDAC INHIBITORS MERCK & CO INC (US) 2009-06-24 EP disclosed
WO-2008033460-A2 TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS SCHERING CORPORATION (US) 2008-03-20 WO disclosed
EP-0676389-B1 Process for preparing O-chloromethyl benzoic acid chloride BASF AG (DE) 1999-09-01 EP disclosed
EP-0676389-A2 Process for preparing O-chloromethyl benzoic acid chloride BASF AKTIENGESELLSCHAFT (DE) 1995-10-11 EP disclosed
US-5224987-A Aqueous carriers with colors and tertiary amide penetrants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170079893-A1 PHASE-STABLE SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS PCNA, MMS19, SUN2 MMP1 4015/4885MMP2 3337/4885MMP3 2042/4885
US-20110082105-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF PHOSPHO1, LIPA, ABHD16A MMP1 3065/4885MMP2 1982/4885MMP3 2274/4885
US-20110081310-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF ABHD16A, LIPA, ABHD12 MMP1 2201/4885MMP2 1741/4885MMP3 2020/4885
US-20170360680-A1 CLEAR SUSPENDING PERSONAL CARE CLEANSING COMPOSITIONS DSG1, CUTA, SNU13 MMP1 1613/4885MMP2 2253/4885MMP3 1958/4885
US-20110081309-A1 COMPOSITIONS COMPRISING A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER AND A MICELLAR THICKENER ABHD16A, DSG1, CUTA MMP1 1361/4885MMP2 2386/4885MMP3 1175/4885
US-20180185263-A1 CLEAR SUSPENDING PERSONAL CARE CLEANSING COMPOSITIONS DSG1, CUTA, SNU13 MMP1 1613/4885MMP2 2253/4885MMP3 1958/4885
US-20170079892-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER MMS19, SUN2, PCNA MMP1 3126/4885MMP2 2656/4885MMP3 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.