Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15441318 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAGAA | |
| SCHEMBL5717721 | 0.78 | MAPT (0.47) | KEAP1NFE2L2POLBNPC1RAB9A | |
| SCHEMBL5189021 | 0.75 | RIPK2 (0.55) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12376647 | 0.71 | PDE4A (0.49) | POLBMAPTGAA | |
| SCHEMBL13101587 | 0.69 | RIPK1 (0.51) | POLBSMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL28391996 | 0.68 | POLB (0.50) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20916997 | 0.68 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1PAX8 | |
| SCHEMBL20917709 | 0.68 | ALDH1A1 (0.40) | POLBSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL169913 | 0.67 | MCL1 (0.65) | ALDH1A1MAPTHTTMCL1 | |
| SCHEMBL18083903 | 0.67 | MAPK1 (0.34) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439428-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2016-09-13 | — | — | US | disclosed |
| US-20150230468-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-20 | — | — | US | disclosed |
| US-9035049-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2015-05-19 | — | — | US | disclosed |
| EP-2694483-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-03-04 | — | — | EP | disclosed |
| EP-2694483-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2014-02-12 | — | — | EP | disclosed |
| US-20140031223-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-01-30 | — | — | US | disclosed |
| WO-2012136703-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2012-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031223-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, RDX | KEAP1 26/4885NFE2L2 2370/4885POLB 4033/4885 |
| US-20150230468-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, RDX | KEAP1 26/4885NFE2L2 2370/4885POLB 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.