Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717721 | 0.78 | MAPT (0.47) | POLBRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2511848 | 0.77 | POLB (0.60) | POLBNPBWR1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10446383 | 0.77 | RAB9A (0.61) | POLBNPBWR1MCHR1RAB9ASMN1; SMN2 | |
| SCHEMBL10941265 | 0.77 | RAB9A (0.61) | POLBNPBWR1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5579308 | 0.75 | POLB (0.57) | POLBRAB9ANPC1NPSR1LMNA | |
| SCHEMBL5189021 | 0.75 | RIPK2 (0.55) | POLBRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30785500 | 0.74 | ALDH1A1 (0.48) | POLBNPBWR1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27158336 | 0.74 | ALDH1A1 (0.43) | POLBNPBWR1MCHR1RAB9ASMN1; SMN2 | |
| SCHEMBL9918817 | 0.73 | ALDH1A1 (0.51) | NPBWR1MCHR1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1750832 | 0.73 | RAB9A (0.70) | POLBNPBWR1MCHR1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111117044-A | Low-fluoride escape irradiation crosslinking polyethylene-tetrafluoroethylene copolymer insulating material and preparation method thereof | 中广核三角洲（江苏）塑化有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111117044-A | Low-fluoride escape irradiation crosslinking polyethylene-tetrafluoroethylene copolymer insulating material and preparation method thereof | 中广核三角洲（江苏）塑化有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111117044-A | Low-fluoride escape irradiation crosslinking polyethylene-tetrafluoroethylene copolymer insulating material and preparation method thereof | 中广核三角洲（江苏）塑化有限公司 | 2020-05-08 | — | — | CN | disclosed |