Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837139 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2F10KDM4EMAPT | |
| SCHEMBL1464894 | 0.79 | CA12 (0.44) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL844453 | 0.79 | OPRM1 (0.53) | ALDH1A1SMN1; SMN2KDM4EMAPTHSD11B1 | |
| SCHEMBL8586765 | 0.78 | KDM4E (0.58) | ALDH1A1SMN1; SMN2KDM4EMAPTMAPK1 | |
| SCHEMBL5878009 | 0.78 | P2RY1 (0.43) | ALDH1A1SMN1; SMN2MAPTMAPK1HSD11B1 | |
| SCHEMBL4678779 | 0.77 | HSD11B1 (0.40) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL349454 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4EMAPTMAPK1 | |
| SCHEMBL20601546 | 0.77 | OPRM1 (0.52) | ALDH1A1SMN1; SMN2MAPTHSD11B1HRH3 | |
| SCHEMBL349353 | 0.77 | HDAC1 (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1DRD2 | |
| SCHEMBL5641709 | 0.77 | OPRM1 (0.52) | ALDH1A1SMN1; SMN2HSD11B1HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138648-A1 | COMPOSITIONS AND METHODS FOR MODULATING LPA RECEPTORS | IRM LLC (BM) | 2012-10-11 | — | — | WO | disclosed |