Cyclooctene

Cyclooctene

SCHEMBL1299542

C1=C/CCCCCC/1.O=C(O)ON1C(=O)CCC1=O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.34
PARL Q9H300 2/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclooctene SCHEMBL1299545 1.00 MGLL (0.34) MGLLPARLCA12CA1CA9
SCHEMBL57128 0.84 PARL (0.38) MGLLPARLCA12CA1CA9
Bicarbonate SCHEMBL28277654 0.82 MGLL (0.36) MGLLPARLCA12CA1CA9
Hno SCHEMBL15321628 0.80 MGLL (0.36) MGLLPARLCA12CA1CA9
SCHEMBL15321160 0.80 MGLL (0.36) MGLLPARLCA12CA1CA9
Oxirane SCHEMBL7945897 0.76 MGLL (0.35) MGLLPARLCA12CA1CA9
Methylene Chloride SCHEMBL28985432 0.76 MGLL (0.36) MGLLPARLCA12CA1CA9
Ethylene Glycol SCHEMBL2577550 0.76 MGLL (0.34) MGLLPARLCA12CA1CA9
SCHEMBL7450429 0.74 MGLL (0.31) MGLLPARL
Diphenylether SCHEMBL1205239 0.73 ALDH1A1 (0.46) MGLLPARLALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030057-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2024-07-09 US disclosed
US-20230234065-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2023-07-27 US disclosed
US-20230065224-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS PLEXIUM INC (US) 2023-03-02 US disclosed
US-11577249-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2023-02-14 US disclosed
EP-4097232-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS Plexium, Inc. (US) 2022-12-07 EP disclosed
US-20220025358-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2022-01-27 US disclosed
US-20210394178-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2021-12-23 US disclosed
US-11084037-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2021-08-10 US disclosed
WO-2021155040-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS Plexium, Inc. (US) 2021-08-05 WO disclosed
US-10981170-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2021-04-20 US disclosed
EP-3687687-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. (US) 2020-08-05 EP disclosed
EP-3622968-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET The General Hospital Corporation (US) 2020-03-18 EP disclosed
EP-2361098-B1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET MASSACHUSETTS GEN HOSPITAL (US) 2019-08-28 EP disclosed
US-20190210018-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. (US) 2019-07-11 US disclosed
US-20190093103-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. (US) 2019-03-28 US disclosed
US-8900549-B2 Compositions and methods for delivering a substance to a biological target THE GENERAL HOSPITAL CORPORATION (US) 2014-12-02 US disclosed
US-20130302246-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION 2013-11-14 US disclosed
US-20110268654-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION (US) 2011-11-03 US disclosed
EP-2361098-A2 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET The General Hospital Corporation (US) 2011-08-31 EP disclosed
WO-2010051530-A2 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION (US) 2010-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110268654-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET FCER2, EPCAM, EPHA2 MGLL 2772/4885PARL 2812/4885CA12 216/4885
US-20130302246-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET FCER2, EPCAM, EPHA2 MGLL 2772/4885PARL 2812/4885CA12 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.