Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12997204 | 0.90 | DNM1 (0.44) | DNM1CA1CA2CA9MAPT | |
| SCHEMBL12997449 | 0.83 | DNM1 (0.43) | DNM1MAPTMAPK1KMT2ACASP6 | |
| SCHEMBL13021555 | 0.80 | DNM1 (0.40) | DNM1CA1CA2CA9MAPT | |
| SCHEMBL12997465 | 0.78 | KCNH2 (0.34) | CA1CA2CA9TERTADRA2A | |
| SCHEMBL15022768 | 0.78 | DNM1 (0.71) | DNM1MAPTMAPK1KMT2ACASP6 | |
| SCHEMBL1435599 | 0.77 | DNM1 (0.45) | DNM1MAPTMAPK1KMT2ACASP6 | |
| SCHEMBL3476002 | 0.77 | DNM1 (0.42) | DNM1CA1CA2CA9MAPT | |
| SCHEMBL15022915 | 0.76 | DNM1 (0.50) | DNM1CA1CA2CA9MAPT | |
| SCHEMBL12997464 | 0.76 | CA1 (0.38) | DNM1CA1CA2CA9ADRA2A | |
| SCHEMBL10494906 | 0.75 | DNM1 (0.43) | DNM1MAPTMAPK1KMT2ACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142777-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |