Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12997204 | 0.93 | DNM1 (0.44) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL12997462 | 0.83 | DNM1 (0.42) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL1435599 | 0.81 | DNM1 (0.45) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL12997212 | 0.79 | DNM1 (0.36) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL15022768 | 0.79 | DNM1 (0.71) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL13020971 | 0.79 | DNM1 (0.40) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL3476002 | 0.78 | DNM1 (0.42) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL15022915 | 0.77 | DNM1 (0.50) | DNM1MAPTMAPK1LMNABLM | |
| SCHEMBL12997452 | 0.77 | S100A4 (0.35) | MAPTMAPK1LMNABLMALDH1A1 | |
| SCHEMBL13021555 | 0.76 | DNM1 (0.40) | DNM1MAPTMAPK1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142777-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |