SCHEMBL1435599

SCHEMBL1435599

O=C1C=C(Nc2ccc(N(CCO)CCO)cc2)C(=O)C=C1NCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 1/20 0.45
▸ ALDH1A1 P00352 6/20 0.41
▸ TDP1 Q9NUW8 3/20 0.41
▸ TSHR P16473 1/20 0.41
▸ MAPT P10636 5/20 0.38
▸ TP53 P04637 2/20 0.38
▸ BLM P54132 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CASP1 P29466 1/20 0.38
▸ CASP7 P55210 1/20 0.38
▸ JAK2 O60674 1/20 0.36
▸ SYK P43405 1/20 0.36
▸ KDM4E B2RXH2 5/20 0.35
▸ APAF1 O14727 3/20 0.35
▸ GAA P10253 3/20 0.35
▸ TDP2 O95551 3/20 0.35
▸ MAPK1 P28482 3/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.35
▸ CASP3 P42574 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948158 0.84 ALDH1A1 (0.40) DNM1ALDH1A1TDP1TSHRMAPT
SCHEMBL12997204 0.82 DNM1 (0.44) DNM1ALDH1A1TDP1MAPTTP53
SCHEMBL15039375 0.81 DNM1 (0.43) DNM1ALDH1A1TDP1MAPTTP53
SCHEMBL12997449 0.81 DNM1 (0.43) DNM1ALDH1A1TDP1MAPTTP53
SCHEMBL15022768 0.81 DNM1 (0.71) DNM1ALDH1A1TDP1MAPTTP53
SCHEMBL15039427 0.80 DNM1 (0.42) DNM1ALDH1A1TDP1MAPTJAK2
SCHEMBL15022915 0.80 DNM1 (0.50) DNM1ALDH1A1TDP1MAPTTP53
SCHEMBL12997462 0.77 DNM1 (0.42) DNM1ALDH1A1TDP1MAPTTP53
SCHEMBL9022771 0.77 ALDH1A1 (0.53) ALDH1A1TDP1TSHRMAPTTP53
SCHEMBL3476002 0.75 DNM1 (0.42) DNM1ALDH1A1TDP1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213444-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS WELLA GERMANY GMBH (DE) 2025-07-03 — — US disclosed
EP-4574216-A2 COMPOSITION FOR ENHANCING KERATIN FIBERS Wella Germany GmbH (DE) 2025-06-25 — — EP disclosed
EP-4499129-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS Wella Germany GmbH (DE) 2025-02-05 — — EP disclosed
US-20240415751-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION WELLA GERMANY GMBH (DE) 2024-12-19 — — US disclosed
US-20240415750-A1 WATER REDUCED COMPACT CONDITIONER COMPOSITION WELLA GERMANY GMBH (DE) 2024-12-19 — — US disclosed
EP-4419067-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION Wella Germany GmbH (DE) 2024-08-28 — — EP disclosed
EP-4419066-A1 WATER REDUCED COMPACT CONDITIONER COMPOSITION Wella Germany GmbH (DE) 2024-08-28 — — EP disclosed
WO-2023180560-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS WELLA GERMANY GMBH (DE) 2023-09-28 — — WO disclosed
WO-2023067176-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION WELLA GERMANY GMBH (DE) 2023-04-27 — — WO disclosed
WO-2023067173-A1 WATER REDUCED COMPACT CONDITIONER COMPOSITION WELLA GERMANY GMBH (DE) 2023-04-27 — — WO disclosed
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORP. 2003-04-10 — — US disclosed
EP-1292267-A2 PHASE-SEPARATED RINSE-OFF HAIR COLORING/CONDITIONING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2003-03-19 — — EP disclosed
EP-1276453-A2 PHASE-SEPARATED RINSE-OFF HAIR COLORING/CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2003-01-22 — — EP disclosed
EP-1246602-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS Ciba SC Holding AG (CH) 2002-10-09 — — EP disclosed
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations HUGLIN DIETMAR (DE) 2002-08-08 — — US disclosed
WO-2001078670-A2 PHASE-SEPARATED RINSE-OFF HAIR COLORING/CONDITIONING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2001-10-25 — — WO disclosed
WO-2001078671-A2 PHASE-SEPARATED RINSE-OFF HAIR COLORING/CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2001-10-25 — — WO disclosed
WO-2001051013-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-07-19 — — WO disclosed
EP-0956851-A1 Use of nanotopes in cosmetic products Ciba SC Holding AG (CH) 1999-11-17 — — EP disclosed
US-4419101-A Chlorine-substituted nitro-para-phenylenediamines, a process for their preparation and their use in dyeing keratin fibres L'OREAL (FR) 1983-12-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213444-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS KRT18, DSG1, CUTA DNM1 4335/4885ALDH1A1 710/4885TDP1 4626/4885
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CUTA, MGLL, TMEM205 DNM1 2373/4885ALDH1A1 1906/4885TDP1 1369/4885
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations NPC1L1, LIPA, CUTA DNM1 2415/4885ALDH1A1 414/4885TDP1 3807/4885
US-20240415751-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION PSAP, POLR1C, AQP3 DNM1 697/4885ALDH1A1 4719/4885TDP1 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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