Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | BLM | P54132 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.39 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.39 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.38 |
| ▸ | APAF1 | O14727 | 5/20 | 0.38 |
| ▸ | CASP3 | P42574 | 5/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 5/20 | 0.38 |
| ▸ | TDP2 | O95551 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022768 | 0.86 | DNM1 (0.71) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL15039541 | 0.86 | DNM1 (0.40) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL15019811 | 0.86 | DNM1 (0.40) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL1435599 | 0.80 | DNM1 (0.45) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL5158945 | 0.79 | MAPT (0.51) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL12997204 | 0.79 | DNM1 (0.44) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL10494906 | 0.77 | DNM1 (0.43) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL12997449 | 0.77 | DNM1 (0.43) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL16272077 | 0.77 | DNM1 (0.37) | DNM1MAPTBLMSMN1; SMN2CYP3A4 | |
| SCHEMBL15039789 | 0.77 | DNM1 (0.35) | DNM1FCGR3BFCGR1AFCGR2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579841-B1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | ORÉAL L (FR) | 2016-09-14 | — | — | EP | disclosed |
| EP-2791106-B1 | PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEROF | OREAL (FR) | 2016-05-18 | — | — | EP | disclosed |
| EP-2579842-B1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED IN THE 4 POSITION WITH A CARBOXYLIC ACID OR AMIDE, AND AT LEAST ONE DIRECT DYE OR A PIGMENT FOR DYEING KERATIN FIBRES | ORÉAL L (FR) | 2016-03-30 | — | — | EP | disclosed |
| US-9233057-B2 | Particular quinone direct dyes, dye composition comprising at least one such dye, implementation process therefor and use thereof | L'OREAL (FR) | 2016-01-12 | — | — | US | disclosed |
| US-20140360523-A1 | PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'OREAL (FR) | 2014-12-11 | — | — | US | disclosed |
| WO-2014191354-A1 | QUINONE DIRECT DYES BEARING A HINDERED ANILINE GROUP, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'OREAL (FR) | 2014-12-04 | — | — | WO | disclosed |
| US-8771376-B2 | Composition comprising at least one 2-pyrrolidone functionalized with an ester or amide radical, and at least one pigment or direct dye, for dyeing keratin materials | L'OREAL (FR) | 2014-07-08 | — | — | US | disclosed |
| US-8585779-B2 | Composition comprising at least one 2-pyrrolidone functionalized in the 4 position with a carboxylic acid or amide, and at least one direct dye or a pigment for dyeing keratin fibres | L'OREAL (FR) | 2013-11-19 | — | — | US | disclosed |
| US-20130167307-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED IN THE 4 POSITION WITH A CARBOXYLIC ACID OR AMIDE, AND AT LEAST ONE DIRECT DYE OR A PIGMENT FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 2013-07-04 | — | — | US | disclosed |
| WO-2013087770-A1 | PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'OREAL (FR) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130167307-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED IN THE 4 POSITION WITH A CARBOXYLIC ACID OR AMIDE, AND AT LEAST ONE DIRECT DYE OR A PIGMENT FOR DYEING KERATIN FIBRES | KRT18, ADH1A, ADH1C | DNM1 1925/4885MAPT 205/4885BLM 4855/4885 |
| US-20140360523-A1 | PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | KRT18, SQOR, NDUFB7 | DNM1 961/4885MAPT 255/4885BLM 2166/4885 |
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | KRT18, ADH1A, ADH5 | DNM1 1690/4885MAPT 254/4885BLM 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.