Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 1.00 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 2/20 | 1.00 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | CASP7 | P55210 | 3/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | MDM4 | O15151 | 1/20 | 0.77 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.77 |
| ▸ | VDR | P11473 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lagodeoxycholate SCHEMBL11967213 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL22415902 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL22415770 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL24001452 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL5150699 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL24032585 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL24124431 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL23781732 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL22778334 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R | |
| Lagodeoxycholate SCHEMBL12575822 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4PDE3ASLC10A2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020895-A1 | Non-Surgical Method of Treatment for Cataract | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-01-26 | — | — | US | disclosed |
| US-20170020895-A1 | Non-Surgical Method of Treatment for Cataract | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-01-26 | — | — | US | disclosed |
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | GOLT1B, NPC1L1, NPC1 | GPBAR1 1566/4885NR1H4 1779/4885PDE3A 3229/4885 |
| US-20170020895-A1 | Non-Surgical Method of Treatment for Cataract | CRYAB, CRYZ, CRYAA | GPBAR1 2473/4885NR1H4 660/4885PDE3A 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.