Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | LPO | P22079 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20696078 | 0.98 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13003012 | 0.87 | BCHE (0.45) | HTR2CNOTUMSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL2116947 | 0.86 | NOTUM (0.44) | HTR2CNOTUMGAALPOCYP1A2 | |
| SCHEMBL6886131 | 0.84 | KMT2A (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23071596 | 0.83 | KDM4E (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20707566 | 0.83 | ALDH1A1 (0.45) | HTR2CNOTUMSMN1; SMN2LPOCYP1A2 | |
| SCHEMBL2115310 | 0.83 | NOTUM (0.65) | NOTUMGAASMN1; SMN2LPOCYP1A2 | |
| SCHEMBL3375069 | 0.82 | TDP1 (0.47) | HTR2CSMN1; SMN2LMNAL3MBTL1HTR6 | |
| SCHEMBL2116949 | 0.82 | KDM4E (0.48) | HTR2CNOTUMLMNAHTR6ALDH1A1 | |
| SCHEMBL3836430 | 0.80 | L3MBTL1 (0.45) | HTR2CNOTUML3MBTL1HTR6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | claimed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | claimed |
| EP-2398760-A1 | ALLOSTERIC BINDING COMPOUNDS | Aarhus Universitet (DK) | 2011-12-28 | — | — | EP | claimed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | claimed |
| JP-56123969-A | — | — | None | — | — | JP | disclosed |
| EP-3661898-B1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2022-02-23 | — | — | EP | disclosed |
| US-11046628-B2 | Process for deoxyfluorination of phenols | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-29 | — | — | US | disclosed |
| US-11046628-B2 | Process for deoxyfluorination of phenols | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-29 | — | — | US | disclosed |
| US-20200369583-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-11-26 | — | — | US | disclosed |
| US-20200369583-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-11-26 | — | — | US | disclosed |
| EP-3438077-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | Studiengesellschaft Kohle mbH (DE) | 2019-02-06 | — | — | EP | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| EP-2398760-A1 | ALLOSTERIC BINDING COMPOUNDS | Aarhus Universitet (DK) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | disclosed |
| JP-S56123969-A | 4-HYDROXYINDOLE DERIVATIVE AND ITS PREPARATION | DAI ICHI PURE CHEM CO LTD | 1981-09-29 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369583-A1 | PROCESS FOR DEOXYFLUORINATION OF PHENOLS | TFEB, MYB, TYR | CA12 807/4885CA1 1211/4885CA2 1903/4885 |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | CA12 4304/4885CA1 2869/4885CA2 1486/4885 |
| US-11046628-B2 | Process for deoxyfluorination of phenols | TFEB, MYB, TYR | CA12 807/4885CA1 1211/4885CA2 1903/4885 |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | CA12 4304/4885CA1 2869/4885CA2 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.