Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | F7 | P08709 | 3/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13562877 | 0.80 | CNR1 (0.61) | ALDH1A1CNR1FAAHMAPTKMT2A | |
| SCHEMBL14752449 | 0.80 | ALDH1A1 (0.36) | ALDH1A1CNR1FAAHOXER1MAPT | |
| SCHEMBL15131732 | 0.80 | MEN1 (0.52) | ALDH1A1CNR1EPHX2KMT2AMAPK1 | |
| SCHEMBL13562881 | 0.79 | CNR1 (0.42) | ALDH1A1CNR1FAAHMAPTEPHX2 | |
| SCHEMBL5323744 | 0.79 | CNR1 (0.49) | CNR1EPHX2KMT2AMEN1 | |
| SCHEMBL5323738 | 0.79 | CNR1 (0.49) | CNR1EPHX2KMT2AMEN1 | |
| SCHEMBL19661057 | 0.78 | MEN1 (0.45) | ALDH1A1CNR1EPHX2KMT2AMEN1 | |
| SCHEMBL12267828 | 0.78 | — | — | |
| SCHEMBL10584847 | 0.78 | — | — | |
| SCHEMBL15951430 | 0.76 | CNR1 (0.70) | ALDH1A1CNR1FAAHMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846972-B2 | Multimeric oleamide derivative having connexin-26 inhibiting potency and use thereof in cancer therapy, etc | The New Industrial Research Organization (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20080089924-A1 | Multimeric Oleamide Derivative Having Connexin-26 Inhibiting Potency and Use Thereof in Cancer Therapy, etc. | THE RITSUMEIKAN TRUST (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080089924-A1 | Multimeric Oleamide Derivative Having Connexin-26 Inhibiting Potency and Use Thereof in Cancer Therapy, etc. | GJA1, GJB2, SLC26A3 | ALDH1A1 1285/4885CNR1 302/4885FAAH 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.