Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951191 | 0.77 | NNMT (0.53) | NNMTGRM5ASIC3PIK3C3ALOX5AP | |
| SCHEMBL6369071 | 0.74 | NNMT (0.51) | NNMTGRM5ASIC3PIK3C3ALOX5AP | |
| SCHEMBL17173410 | 0.73 | NNMT (0.49) | NNMTPIK3C3 | |
| SCHEMBL13533931 | 0.73 | AHR (0.41) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL14026564 | 0.72 | GRM5 (0.40) | NNMTGRM5ASIC3PIK3C3ALOX5AP | |
| SCHEMBL17173454 | 0.72 | KMT2A (0.49) | NNMTGRM5PIK3C3 | |
| SCHEMBL24765213 | 0.71 | ADRA2A (0.52) | NNMTGRM5ASIC3PIK3C3ALOX5AP | |
| SCHEMBL620335 | 0.71 | CHRNB2 (0.48) | NNMTGRM5ASIC3PIK3C3ALOX5AP | |
| SCHEMBL14158455 | 0.70 | NNMT (0.49) | NNMTGRM5ASIC3PIK3C3ALOX5AP | |
| SCHEMBL6425767 | 0.68 | NNMT (0.55) | NNMTGRM5ASIC3PIK3C3ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633750-B1 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES | EISAI R&D MAN CO LTD (JP) | 2010-12-01 | — | — | EP | disclosed |