Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390084 | 0.90 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2BCL2L1GABRA1GABRB1 | |
| SCHEMBL3330717 | 0.87 | BCL2L1 (0.45) | ALDH1A1SMN1; SMN2BCL2L1MAPTLMNA | |
| SCHEMBL15774677 | 0.87 | HSD17B2 (0.52) | ALDH1A1SMN1; SMN2BCL2L1MAPTATM | |
| SCHEMBL13057678 | 0.87 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2BCL2L1GABRA1GABRB1 | |
| SCHEMBL16479442 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2BCL2L1MAPTLMNA | |
| SCHEMBL16474350 | 0.85 | LMNA (0.50) | ALDH1A1SMN1; SMN2BCL2L1MAPTLMNA | |
| SCHEMBL2807973 | 0.85 | TSHR (0.45) | ALDH1A1SMN1; SMN2BCL2L1MAPTLMNA | |
| SCHEMBL3328123 | 0.83 | HTT (0.48) | ALDH1A1SMN1; SMN2BCL2L1MAPTCA12 | |
| SCHEMBL14217542 | 0.82 | KDM4E (0.51) | ALDH1A1SMN1; SMN2MAPTLMNACA12 | |
| SCHEMBL2932838 | 0.81 | BCL2L1 (0.53) | ALDH1A1SMN1; SMN2BCL2L1GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102652-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2015-08-11 | — | — | US | disclosed |
| US-9102652-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2015-08-11 | — | — | US | disclosed |
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED (US) | 2014-07-17 | — | — | US | disclosed |
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED (US) | 2014-07-17 | — | — | US | disclosed |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | NR0B2, NR0B1, DHCR24 | ALDH1A1 1991/4885SMN1; SMN2 3498/4885BCL2L1 2974/4885 |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | NR0B2, NR0B1, NR2E3 | ALDH1A1 1833/4885SMN1; SMN2 3654/4885BCL2L1 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.