Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 15/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061014 | 0.86 | CALM1 (0.58) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005561 | 0.78 | CALM1 (0.52) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005440 | 0.77 | CALM1 (0.59) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL4823756 | 0.77 | KDM4E (0.65) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005546 | 0.74 | CALM1 (0.47) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL524817 | 0.74 | CALM1 (0.65) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005713 | 0.73 | CALM1 (0.46) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005498 | 0.73 | CALM1 (0.46) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005637 | 0.73 | CALM1 (0.52) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL10147148 | 0.73 | CALM1 (0.53) | CALM1CAMKK2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |