Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060646 | 0.89 | FYN (0.52) | FYNPRKD3PRKD1PRKD2RAD52 | |
| SCHEMBL17154227 | 0.88 | FYN (0.49) | FYNPRKD3PRKD1PRKD2RAD52 | |
| SCHEMBL13005472 | 0.83 | CTSL (0.41) | — | |
| SCHEMBL13005481 | 0.83 | CTSL (0.41) | — | |
| SCHEMBL13005536 | 0.82 | ROCK2 (0.40) | — | |
| SCHEMBL13005534 | 0.82 | ROCK2 (0.40) | — | |
| SCHEMBL13005444 | 0.82 | KCNA5 (0.51) | FYN | |
| SCHEMBL17154234 | 0.80 | UTS2R (0.46) | PRKD3PRKD1PRKD2MAP4K4PARP1 | |
| SCHEMBL13005693 | 0.80 | ROCK2 (0.50) | — | |
| SCHEMBL17155168 | 0.79 | CAMK2D (0.52) | FYNPRKD3PRKD1PRKD2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |