Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 4/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005451 | 0.89 | FYN (0.51) | FYNPRKD3PRKD1PRKD2HCRTR2 | |
| SCHEMBL17155168 | 0.87 | CAMK2D (0.52) | FYNPRKD3PRKD1PRKD2MAP4K4 | |
| SCHEMBL13061005 | 0.80 | KCNA5 (0.49) | — | |
| SCHEMBL13060890 | 0.79 | CTSL (0.41) | — | |
| SCHEMBL13060892 | 0.79 | CTSL (0.41) | — | |
| SCHEMBL13060800 | 0.79 | TAS1R3 (0.41) | — | |
| SCHEMBL13061114 | 0.79 | TAS1R3 (0.41) | — | |
| SCHEMBL17154227 | 0.79 | FYN (0.49) | FYNPRKD3PRKD1PRKD2MAP4K4 | |
| SCHEMBL17155484 | 0.79 | PRKD3 (0.48) | PRKD3PRKD1PRKD2MAP4K4CAMK2D | |
| SCHEMBL17066988 | 0.78 | FYN (0.52) | FYNPRKD3PRKD1PRKD2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |