Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005518 | 0.87 | CETP (0.40) | ALDH1A1CETPSLC6A2SLC6A3TAAR1 | |
| SCHEMBL13005520 | 0.86 | LMNA (0.37) | KDM4ECETPSLC6A2SLC6A3TAAR1 | |
| SCHEMBL13005522 | 0.86 | CETP (0.36) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13005507 | 0.86 | TAAR1 (0.34) | CETPTAAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13005500 | 0.86 | GABRA1 (0.39) | CETPPOLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13005616 | 0.84 | BCHE (0.40) | CETPSLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL13005513 | 0.84 | CETP (0.32) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13005611 | 0.84 | CETP (0.34) | ALDH1A1KDM4ECETPSMN1; SMN2GRIN2D | |
| SCHEMBL13005613 | 0.84 | GAA (0.39) | ALDH1A1KDM4ECETPMEN1KMT2A | |
| SCHEMBL13005641 | 0.83 | SLC6A4 (0.41) | CETPSLC6A2SLC6A3GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |