Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005722 | 0.90 | CALM1 (0.48) | TAAR1CALM1CAMKK2MEN1KMT2A | |
| SCHEMBL13005440 | 0.87 | CALM1 (0.59) | TAAR1CALM1CAMKK2SLC6A3SLC6A2 | |
| SCHEMBL13005625 | 0.85 | BCHE (0.47) | TAAR1CALM1CAMKK2SLC6A3SLC6A2 | |
| SCHEMBL13005633 | 0.85 | CALM1 (0.40) | TAAR1CALM1CAMKK2SLC6A3SLC6A2 | |
| SCHEMBL13005676 | 0.84 | CALM1 (0.45) | TAAR1CALM1CAMKK2SLC6A3SLC6A2 | |
| SCHEMBL13060692 | 0.84 | TAAR1 (0.57) | TAAR1CALM1CAMKK2SLC6A3MEN1 | |
| SCHEMBL13005692 | 0.83 | TSHR (0.54) | TAAR1CALM1CAMKK2RIPK1ALDH1A1 | |
| SCHEMBL13005702 | 0.83 | TAAR1 (0.53) | TAAR1CALM1CAMKK2MEN1KMT2A | |
| SCHEMBL13005720 | 0.83 | OPRK1 (0.49) | CALM1CAMKK2MEN1KMT2AOPRM1 | |
| SCHEMBL13005575 | 0.83 | CALM1 (0.41) | TAAR1CALM1CAMKK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |