Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005440 | 0.87 | CALM1 (0.59) | TSHRTAAR1CALM1CAMKK2ALDH1A1 | |
| SCHEMBL13005603 | 0.86 | CALM1 (0.44) | TSHRRECQLTAAR1PNMTAOC3 | |
| SCHEMBL13005625 | 0.85 | BCHE (0.47) | TSHRRECQLTAAR1AOC3CALM1 | |
| SCHEMBL13005661 | 0.84 | CALM1 (0.45) | TSHRRECQLTAAR1AOC3CALM1 | |
| SCHEMBL13061026 | 0.84 | TAAR1 (0.57) | TSHRRECQLTAAR1PNMTAOC3 | |
| SCHEMBL4823754 | 0.84 | CALM1 (0.62) | TSHRRECQLTAAR1AOC3CALM1 | |
| SCHEMBL13005684 | 0.83 | TAAR1 (0.53) | TAAR1CALM1CAMKK2RIPK1ALDH1A1 | |
| SCHEMBL13005720 | 0.83 | OPRK1 (0.49) | CALM1CAMKK2 | |
| SCHEMBL13005702 | 0.83 | TAAR1 (0.53) | TSHRRECQLTAAR1CALM1CAMKK2 | |
| SCHEMBL13005422 | 0.83 | CALM1 (0.48) | TSHRRECQLTAAR1CALM1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |