Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 16/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 15/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005432 | 0.99 | OPRM1 (0.44) | OPRM1OPRK1OPRD1CALM1CAMKK2 | |
| SCHEMBL13005541 | 0.89 | OPRM1 (0.44) | OPRM1OPRK1OPRD1CXCR4 | |
| SCHEMBL13005558 | 0.85 | KDM4E (0.54) | OPRM1OPRK1OPRD1CALM1CAMKK2 | |
| SCHEMBL172762 | 0.85 | OPRM1 (0.47) | OPRM1OPRK1OPRD1CALM1CAMKK2 | |
| SCHEMBL13061009 | 0.83 | OPRM1 (0.46) | OPRM1OPRK1OPRD1CALM1CAMKK2 | |
| SCHEMBL13005529 | 0.82 | CXCR4 (0.57) | OPRM1OPRK1OPRD1CXCR4 | |
| SCHEMBL13005625 | 0.81 | BCHE (0.47) | OPRM1OPRK1OPRD1CALM1CAMKK2 | |
| SCHEMBL13005441 | 0.81 | LTA4H (0.47) | OPRM1OPRK1OPRD1 | |
| SCHEMBL10039132 | 0.80 | OPRM1 (0.54) | OPRM1OPRK1OPRD1CALM1CAMKK2 | |
| SCHEMBL13005440 | 0.80 | CALM1 (0.59) | OPRM1OPRK1OPRD1CALM1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |