Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.46 |
| ▸ | WDR5 | P61964 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445385 | 0.93 | LMNA (0.53) | LMNAPOLBCHRM3NPSR1CHRM2 | |
| SCHEMBL303303 | 0.93 | LMNA (0.53) | LMNAPOLBCHRM3NPSR1CHRM2 | |
| SCHEMBL13006415 | 0.92 | LMNA (0.55) | LMNAPOLBCHRM3NPSR1WDR5 | |
| SCHEMBL302660 | 0.92 | LMNA (0.53) | LMNAPOLBCHRM3NPSR1WDR5 | |
| SCHEMBL29505154 | 0.92 | LMNA (0.53) | LMNAPOLBCHRM3NPSR1WDR5 | |
| SCHEMBL1136177 | 0.91 | LMNA (0.64) | LMNAPOLBCHRM3NPSR1CHRM2 | |
| SCHEMBL1144935 | 0.91 | LMNA (0.53) | LMNAPOLBCHRM3NPSR1WDR5 | |
| SCHEMBL16618150 | 0.90 | LMNA (0.63) | LMNAPOLBCHRM3NPSR1CHRM2 | |
| SCHEMBL1136137 | 0.89 | LMNA (0.54) | LMNAPOLBCHRM3NPSR1WDR5 | |
| SCHEMBL29445400 | 0.87 | LMNA (0.48) | LMNAPOLBCHRM3NPSR1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490342-B1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | LMNA 4600/4885POLB 1757/4885CHRM3 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.