SCHEMBL303303

SCHEMBL303303

Cn1cc(C(=O)Nc2ccc(F)cc2-c2ccc(Cl)c(Cl)c2)c(C(F)(F)F)n1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
CHRM3 P20309 11/20 0.50
CHRM2 P08172 2/20 0.44
CHRM1 P11229 2/20 0.44
WDR5 P61964 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
STING1 Q86WV6 1/20 0.41
NTRK1 P04629 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445385 1.00 LMNA (0.53) LMNAPOLBCHRM3CHRM2CHRM1
SCHEMBL29505154 0.93 LMNA (0.53) LMNAPOLBCHRM3WDR5NPSR1
SCHEMBL302660 0.93 LMNA (0.53) LMNAPOLBCHRM3WDR5NPSR1
SCHEMBL13006282 0.93 LMNA (0.55) LMNAPOLBCHRM3CHRM2CHRM1
SCHEMBL29445431 0.92 LMNA (0.53) LMNAPOLBCHRM3WDR5NPSR1
SCHEMBL1402183 0.92 LMNA (0.53) LMNAPOLBCHRM3WDR5NPSR1
SCHEMBL1136177 0.90 LMNA (0.64) LMNAPOLBCHRM3CHRM2CHRM1
SCHEMBL14553393 0.90 LMNA (0.49) LMNAPOLBCHRM3WDR5NPSR1
SCHEMBL1136137 0.90 LMNA (0.54) LMNAPOLBCHRM3WDR5NPSR1
SCHEMBL16618150 0.89 LMNA (0.63) LMNAPOLBCHRM3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
WO-2016109396-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2016-07-07 WO claimed
US-20100016156-A1 Pesticidal Mixtures BASF SE (DE) 2010-01-21 US claimed
EP-2131658-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2009-12-16 EP claimed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 EP claimed
EP-2061320-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2009-05-27 EP claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 WO claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO claimed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 WO claimed
WO-2008092836-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2008-08-07 WO claimed
EP-1952691-A2 Method for improving plant health by application of a triazolopyrimidine derivative BASF SE (DE) 2008-08-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016156-A1 Pesticidal Mixtures PFN1, CYP4X1, PFAS LMNA 1358/4885POLB 2126/4885CHRM3 166/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC LMNA 3370/4885POLB 2674/4885CHRM3 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.