SCHEMBL16618150

SCHEMBL16618150

Cn1cc(C(=O)Nc2ccc(F)cc2-c2ccc(Cl)cc2)c(C(F)(F)F)n1.Cn1cc(C(=O)Nc2ccc(F)cc2-c2ccc(F)cc2)c(C(F)(F)F)n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
POLB P06746 1/20 0.63
NPSR1 Q6W5P4 2/20 0.50
CHRM3 P20309 6/20 0.48
PSEN1 P49768 1/20 0.45
PSEN2 P49810 1/20 0.45
APH1B Q8WW43 1/20 0.45
NCSTN Q92542 1/20 0.45
APH1A Q96BI3 1/20 0.45
PSENEN Q9NZ42 1/20 0.45
CSNK1D P48730 3/20 0.45
CSNK1E P49674 3/20 0.45
NTRK1 P04629 1/20 0.44
WDR5 P61964 2/20 0.44
CHRM2 P08172 1/20 0.42
CHRM1 P11229 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
TAS1R2 Q8TE23 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1136177 0.99 LMNA (0.64) LMNAPOLBNPSR1CHRM3PSEN1
SCHEMBL1136137 0.95 LMNA (0.54) LMNAPOLBNPSR1CHRM3NTRK1
SCHEMBL13006282 0.90 LMNA (0.55) LMNAPOLBNPSR1CHRM3WDR5
SCHEMBL1136025 0.90 LMNA (0.51) LMNAPOLBNPSR1CHRM3NTRK1
SCHEMBL303303 0.89 LMNA (0.53) LMNAPOLBNPSR1CHRM3NTRK1
SCHEMBL29445385 0.89 LMNA (0.53) LMNAPOLBNPSR1CHRM3NTRK1
SCHEMBL1144935 0.89 LMNA (0.53) LMNAPOLBNPSR1CHRM3NTRK1
SCHEMBL13491717 0.89 LMNA (0.52) LMNAPOLBCHRM3NTRK1WDR5
SCHEMBL29505154 0.88 LMNA (0.53) LMNAPOLBNPSR1CHRM3NTRK1
SCHEMBL302660 0.88 LMNA (0.53) LMNAPOLBNPSR1CHRM3NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
EP-4282272-A2 METHOD OF DELIVERING AN AGRICULTURALLY ACTIVE INGREDIENT FMC Corporation (US) 2023-11-29 EP disclosed
EP-4234724-A2 BACILLUS THURINGIENSIS RTI545 COMPOSITIONS AND METHODS OF USE FOR BENEFITTING PLANT GROWTH AND CONTROLLING PLANT PESTS FMC Agricultural Solutions A/S (DK) 2023-08-30 EP disclosed
EP-3522706-B1 BACILLUS THURINGIENSIS RTI545 COMPOSITIONS AND METHODS OF USE FOR BENEFITTING PLANT GROWTH AND CONTROLLING PLANT PESTS FMC AGRICULTURAL SOLUTIONS AS (DK) 2023-06-07 EP disclosed
EP-4046491-A1 INSECT REPELLENT FMC Corporation (US) 2022-08-24 EP disclosed
US-20200296956-A1 FOAM FORMULATIONS AND APPARATUS FOR DELIVERY FMC CORPORATION 2020-09-24 US disclosed
EP-3240403-B1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORP (US) 2019-11-13 EP disclosed
EP-3160226-A1 FOAM FORMULATIONS AND EMULSIFIABLE CONCENTRATES FMC CORPORATION (US) 2017-05-03 EP disclosed
US-20160249620-A1 Alginate Coating for Seed Treatment FMC CORP (US) 2016-09-01 US disclosed
WO-2015200428-A1 FOAM FORMULATIONS AND EMULSIFIABLE CONCENTRATES FMC CORPORATION (US) 2015-12-30 WO disclosed
US-20150216173-A1 METHODS FOR CONTROLLING WEEDS USING FORMULATIONS CONTAINING FLUTHIACET-METHYL AND HPPD HERBICIDES FMC CORPORATION (US) 2015-08-06 US disclosed
US-20150099627-A1 Co-Formulations of Bifenthrin with Encapsulated Crop Protection Agents For Use with Liquid Fertilizers FMC CORPORATION (US) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC LMNA 3370/4885POLB 2674/4885NPSR1 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.