⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526123 | 0.78 | USP2 (0.40) | — | |
| SCHEMBL483180 | 0.78 | — | — | |
| SCHEMBL389739 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL29689430 | 0.76 | — | — | |
| SCHEMBL368150 | 0.74 | MAPT (0.37) | — | |
| SCHEMBL860227 | 0.74 | HRH1 (0.41) | — | |
| SCHEMBL15310285 | 0.74 | TDP1 (0.36) | — | |
| SCHEMBL1327604 | 0.74 | — | — | |
| SCHEMBL10437043 | 0.73 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL2795198 | 0.73 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040068107-A1 | Method for the production of pentopyranosly nucleosides | KRETSCHMAR GERHARD (DE) | 2004-04-08 | — | — | US | claimed |
| CN-107721958-B | Novel compounds and compositions for targeting cancer stem cells | 北京强新生物科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| EP-2547205-B1 | NOVEL METHODS FOR TARGETING CANCER STEM CELLS | 1GLOBE BIOMEDICAL CO LTD (CN) | 2024-03-20 | — | — | EP | disclosed |
| CN-107375260-B | Novel compounds and compositions for targeting cancer stem cells | 北京强新生物科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-107311969-B | Novel compounds and compositions for targeting cancer stem cells | 北京强新生物科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20200397740-A1 | 2-ACETYLNAPHTHO[2,3-B]FURAN -4,9-DIONE FOR USE ON TREATING CANCER | Sumitomo Dainnipon Pharma Oncology. Inc. (US) | 2020-12-24 | — | — | US | disclosed |
| US-10543189-B2 | 2-acetylnaphtho[2,3-b]furan -4,9-dione for use on treating cancer | BOSTON BIOMEDICAL, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-20180193303-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | BOSTON BIOMEDICAL INC (US) | 2018-07-12 | — | — | US | disclosed |
| EP-3108750-B1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | 1GLOBE BIOMEDICAL CO LTD (CN) | 2018-07-04 | — | — | EP | disclosed |
| EP-3295796-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | 1Globe Biomedical Co., Ltd. (CN) | 2018-03-21 | — | — | EP | disclosed |
| US-4822788-A | MICROBIOCIDES, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0053816-B1 | 1-SULFO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1988-05-04 | — | — | EP | disclosed |
| US-4675397-A | MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-06-23 | — | — | US | disclosed |
| US-4665067-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4550105-A | BETA-LACTAMASE INHIBITORS, ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |
| EP-0053816-A1 | 1-Sulfo-2-oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| US-4238391-A | AMIDATION OF BLEOMYCINIC ACID | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-12-09 | — | — | US | disclosed |
| US-4195018-A | CARCINOSTATIC ANTIBIOTICS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-03-25 | — | — | US | disclosed |