SCHEMBL1300786

SCHEMBL1300786

CCCC(N)(CCCC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP1A2 P05177 1/20 0.57
THRB P10828 1/20 0.57
AKR1B1 P15121 1/20 0.46
GPR84 Q9NQS5 7/20 0.45
PPARG P37231 7/20 0.45
PPARD Q03181 7/20 0.45
PPARA Q07869 7/20 0.45
HDAC11 Q96DB2 5/20 0.45
TSHR P16473 4/20 0.45
PTPN1 P18031 3/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
SLC22A8 Q8TCC7 1/20 0.45
ESR1 P03372 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423249 0.92 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL1399007 0.88 ALDH1A1 (0.73) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL9005565 0.88 ALDH1A1 (0.73) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL1300539 0.86 ALDH1A1 (0.77) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL23010905 0.85 ARG1 (0.48) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL348479 0.85 MEN1 (0.54) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL9005521 0.84 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL20156725 0.83 ARG2 (0.52) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL27645402 0.82 ALDH1A1 (0.66) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL31678259 0.82 ARG2 (0.50) ALDH1A1MEN1KMT2ACYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699242-B1 CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF ALFAMA INC (US) 2017-11-01 EP disclosed
US-9023636-B2 Microorganisms and methods for the biosynthesis of propylene GENOMATICA, INC. (US) 2015-05-05 US disclosed
US-8617862-B2 Microorganisms for producing propylene and methods related thereto GENOMATICA, INC. (US) 2013-12-31 US disclosed
EP-2563926-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE Genomatica, Inc. (US) 2013-03-06 EP disclosed
US-20120329119-A1 MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO GENOMATICA, INC. 2012-12-27 US disclosed
WO-2011137198-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE GENOMATICA, INC. (US) 2011-11-03 WO disclosed
US-20110269204-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE AGAIN BIO APS (DK) 2011-11-03 US disclosed
EP-1280760-B1 NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF CURRY KENNETH (CA) 2004-04-28 EP disclosed
EP-1280760-A1 NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF Curry, Kenneth (CA) 2003-02-05 EP disclosed
WO-2001085669-A1 NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF CURRY KENNETH (CA) 2001-11-15 WO disclosed