Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725425 | 0.89 | DRD3 (0.78) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL12665435 | 0.88 | DRD3 (0.61) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| Pefloxacin SCHEMBL28251251 | 0.88 | DRD3 (1.00) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| Pefloxacin SCHEMBL29351730 | 0.88 | DRD3 (1.00) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11022945 | 0.88 | DRD3 (0.77) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6664468 | 0.88 | DRD3 (0.77) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| Pefloxacin SCHEMBL34292 | 0.88 | DRD3 (1.00) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL26017160 | 0.88 | KDM4E (0.78) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| Pefloxacin SCHEMBL8184732 | 0.87 | DRD3 (0.98) | DRD3KDM4EMEN1KMT2AALDH1A1 | |
| Pefloxacin SCHEMBL9800276 | 0.87 | DRD3 (0.98) | DRD3KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233559-A1 | COMBINATION OF ZIDOVUDINE AND FLUOROQUINOLONE ANTIBIOTIC | HELPERBY THERAPEUTICS LIMITED (GB) | 2023-07-27 | — | — | US | disclosed |
| US-20100317624-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233559-A1 | COMBINATION OF ZIDOVUDINE AND FLUOROQUINOLONE ANTIBIOTIC | DUT, DPYD, IMPDH1 | DRD3 949/4885KDM4E 1132/4885MEN1 4396/4885 |
| US-20100317624-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | UROD, UMPS, SLC14A1 | DRD3 3281/4885KDM4E 2695/4885MEN1 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.