Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493222 | 0.87 | MAPT (0.47) | MAPTTSHRPDE3BPDE3AP2RY12 | |
| SCHEMBL13008062 | 0.87 | LMNA (0.39) | MAPTTSHRPDE3BPDE3AP2RY12 | |
| SCHEMBL10202996 | 0.83 | LMNA (0.59) | MAPTLMNAALDH1A1LTA4HKDM4E | |
| SCHEMBL13008056 | 0.83 | MCL1 (0.47) | TSHRLMNAGAAPOLBPPARG | |
| SCHEMBL15307916 | 0.83 | CNR2 (0.40) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL13224018 | 0.82 | PDE3B (0.44) | MAPTTSHRPDE3BPDE3AP2RY12 | |
| SCHEMBL13490815 | 0.80 | BRD4 (0.47) | TSHRPDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL23843414 | 0.79 | MAPT (0.49) | MAPTTSHRPDE3BPDE3AP2RY12 | |
| SCHEMBL13224055 | 0.79 | MAPT (0.41) | MAPTTSHRPDE3BPDE3AP2RY12 | |
| SCHEMBL13463051 | 0.79 | KDM4E (0.60) | TSHRALDH1A1KDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404678-B2 | Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use | SANOFI (FR) | 2013-03-26 | — | — | US | disclosed |
| US-20100316656-A1 | CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE | SANOFI-AVENTIS (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316656-A1 | CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE | TOMM34, TOMM70, TOMM40 | MAPT 3353/4885TSHR 2636/4885PDE3B 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.