Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CHKA | P35790 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594145 | 0.95 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBTDP1CHKA | |
| SCHEMBL9966080 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBTDP1GAA | |
| SCHEMBL1594835 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTDP1GAA | |
| SCHEMBL15905581 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTDP1GAA | |
| SCHEMBL1594036 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTDP1GAA | |
| SCHEMBL1594222 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| SCHEMBL14953395 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBTDP1GAA | |
| SCHEMBL12620551 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| SCHEMBL4244410 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| SCHEMBL1594602 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317648-A1 | THERAPEUTIC COMPOUNDS | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2010-12-16 | — | — | US | disclosed |
| US-20100317648-A1 | THERAPEUTIC COMPOUNDS | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317648-A1 | THERAPEUTIC COMPOUNDS | MAOB, MAOA, HTR1B | ALDH1A1 455/4885KDM4E 731/4885POLB 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.