SCHEMBL1594835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15905581	0.92	ALDH1A1 (0.46)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL1594222	0.91	ALDH1A1 (0.47)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL1594145	0.88	ALDH1A1 (0.48)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL9966080	0.88	ALDH1A1 (0.48)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL1594036	0.85	ALDH1A1 (0.46)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL13008472	0.84	ALDH1A1 (0.46)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL14953395	0.83	ALDH1A1 (0.47)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL12620551	0.79	ALDH1A1 (0.55)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL1594367	0.78	ALDH1A1 (0.53)	ALDH1A1GAAPOLBL3MBTL1PTGES2
	SCHEMBL5661712	0.77	DRD2 (0.50)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.