SCHEMBL13010041

SCHEMBL13010041

COc1ccc(C(OCC2OC(n3ccc(=O)[nH]c3=O)C(O[Si](C)(C)C(C)(C)C)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.51
P2RY14 Q15391 4/20 0.47
P2RY2 P41231 9/20 0.43
P2RY6 Q15077 7/20 0.43
P2RY4 P51582 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363037 1.00 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL20503186 1.00 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL17223118 1.00 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL1582059 1.00 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL19692972 0.91 TYMP (0.45) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL19709161 0.91 TYMP (0.45) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL19709156 0.91 TYMP (0.45) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL6284697 0.90 TYMP (0.53) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL20828930 0.90 TYMP (0.53) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL19709160 0.90 TYMP (0.53) TYMPP2RY14P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2233573-B1 A COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS SUZHOU RIBO LIFE SCIENCE CO LTD (CN) 2013-10-23 EP disclosed
US-20100317714-A1 COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317714-A1 COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS DCLRE1B, RNASE1, AGO2 TYMP 1836/4885P2RY14 4508/4885P2RY2 4452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.