Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 7/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9288054 | 0.82 | CYP1A2 (0.53) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL12200891 | 0.81 | CYP1A2 (0.56) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL13989582 | 0.77 | CA2 (0.44) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL16674725 | 0.76 | CA2 (0.45) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL11888406 | 0.76 | CYP1A2 (0.61) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL1645476 | 0.75 | CA2 (0.52) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL13010060 | 0.75 | CA2 (0.39) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL11129970 | 0.73 | KMT2A (0.47) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL13989597 | 0.73 | HDAC6 (0.44) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL16669352 | 0.72 | CA2 (0.49) | CA2CYP1A2CYP2C19HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |
| EP-2233573-A1 | A COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | Suzhou Ribo Life Science Co., Ltd (CN) | 2010-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | DCLRE1B, RNASE1, AGO2 | CA2 4108/4885CYP1A2 4731/4885CYP2C19 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.