Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 7/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338547 | 1.00 | TYMP (0.41) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL9208332 | 0.86 | TYMP (0.44) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL10423328 | 0.86 | TYMP (0.44) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL9212681 | 0.86 | TYMP (0.44) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL13329987 | 0.81 | TYMP (0.45) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL13255807 | 0.81 | TYMP (0.45) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL13374762 | 0.81 | TYMP (0.45) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL13190443 | 0.81 | SLC6A11 (0.40) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL12601445 | 0.80 | TYMP (0.44) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL14062514 | 0.80 | TYMP (0.44) | TYMPSLC6A11SLC6A1SLC6A12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) | 2010-12-16 | — | — | US | disclosed |
| EP-2233573-A1 | A COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | Suzhou Ribo Life Science Co., Ltd (CN) | 2010-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317714-A1 | COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS | DCLRE1B, RNASE1, AGO2 | TYMP 1836/4885SLC6A11 4837/4885SLC6A1 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.