Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 6/20 | 1.00 |
| ▸ | APP | P05067 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 1/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 1/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 1/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 1/20 | 1.00 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 1/20 | 1.00 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 1.00 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 1.00 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorogenic Acid SCHEMBL19466 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL22111591 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL13250699 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL24239743 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL21191546 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL24879283 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL21433650 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL22422499 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL21142437 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 | |
| Chlorogenic Acid SCHEMBL14534395 | 1.00 | AKR1B1 (1.00) | AKR1B1PTPN1APPHSD17B10AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578222-A1 | Plant extract composition | Lanwehr, Christoph Alexander Bernhard (DE) | 2013-04-10 | — | — | EP | claimed |
| US-20250002490-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2025-01-02 | — | — | US | disclosed |
| US-11976063-B2 | Pharmaceutical composition comprising berberine and ursodeoxycholic acid for the treatment of various diseases or disorders | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2024-05-07 | — | — | US | disclosed |
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-11685735-B2 | Pharmaceutical composition comprising berberine salts for the treatment of various diseases or disorders | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
| US-11324244-B2 | Potato derived flavour enhancing composition and method for the manufacture thereof | CONOPCO INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-20210300915-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2021-09-30 | — | — | US | disclosed |
| US-10988471-B2 | Pharmaceutical composition comprising berberine ursodeoxycholic acid salt for the treatment of various diseases or disorders | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| EP-3174874-B1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2020-09-02 | — | — | EP | disclosed |
| WO-2016046680-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER METABOLIC DISEASES | MOHAN M ALAPATI (IN) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016046679-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DIABETES AND PRE-DIABETES | MOHAN M ALAPATI (IN) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016046670-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF RENAL DISEASES | MOHAN M ALAPATI (IN) | 2016-03-31 | — | — | WO | disclosed |
| US-20160081364-A1 | PAR-BAKED AND MILLED COFFEE BEANS FOR USE IN FOODS, BEVERAGES AND DIETARY SUPPLEMENTS | BRANDEIS UNIVERSITY | 2016-03-24 | — | — | US | disclosed |
| WO-2015009481-A2 | PAR-BAKED AND MILLED COFFEE BEANS FOR USE IN FOODS, BEVERAGES AND DIETARY SUPPLEMENTS | BRANDEIS UNIVERSITY (US) | 2015-01-22 | — | — | WO | disclosed |
| WO-2015000606-A1 | POTATO DERIVED FLAVOUR ENHANCING COMPOSITION AND METHOD FOR THE MANUFACTURE THEREOF | UNILEVER N.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| EP-2578222-A1 | Plant extract composition | Lanwehr, Christoph Alexander Bernhard (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20100323033-A1 | CANCER SENSITIZER COMPRISING CHLOROGENIC ACID | NATIONAL CANCER CENTER (KR) | 2010-12-23 | — | — | US | disclosed |
| US-20100173990-A1 | Transglutaminase Inhibitor Comprising Chlorogenic Acid And A Method For Producing Thereof | NATIONAL CANCER CENTER (KR) | 2010-07-08 | — | — | US | disclosed |
| US-20100173990-A1 | Transglutaminase Inhibitor Comprising Chlorogenic Acid And A Method For Producing Thereof | NATIONAL CANCER CENTER (KR) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | AKR1B1 183/4885PTPN1 3843/4885APP 1094/4885 |
| US-20250002490-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | AKR1B1 183/4885PTPN1 3843/4885APP 1094/4885 |
| US-10988471-B2 | Pharmaceutical composition comprising berberine ursodeoxycholic acid salt for the treatment of various diseases or disorders | CYP27A1, SLC10A1, NR1H4 | AKR1B1 208/4885PTPN1 2842/4885APP 1161/4885 |
| US-20210300915-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | AKR1B1 183/4885PTPN1 3843/4885APP 1094/4885 |
| US-20100323033-A1 | CANCER SENSITIZER COMPRISING CHLOROGENIC ACID | ABCC1, KEAP1, SLC11A2 | AKR1B1 278/4885PTPN1 948/4885APP 4561/4885 |
| US-11685735-B2 | Pharmaceutical composition comprising berberine salts for the treatment of various diseases or disorders | CPT1B, CYP27A1, GLS2 | AKR1B1 108/4885PTPN1 3728/4885APP 650/4885 |
| US-20100173990-A1 | Transglutaminase Inhibitor Comprising Chlorogenic Acid And A Method For Producing Thereof | GAA, TGM2, CMBL | AKR1B1 1659/4885PTPN1 3115/4885APP 3589/4885 |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | AKR1B1 183/4885PTPN1 3843/4885APP 1094/4885 |
| US-11976063-B2 | Pharmaceutical composition comprising berberine and ursodeoxycholic acid for the treatment of various diseases or disorders | CYP27A1, NR1H4, CPT1B | AKR1B1 171/4885PTPN1 3817/4885APP 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.