Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12169769 | 0.85 | AOC3 (0.51) | AOC3SIGMAR1ALOX5CHRM2HTR1A | |
| SCHEMBL10127403 | 0.81 | HDAC1 (0.52) | AOC3SIGMAR1ALOX5 | |
| SCHEMBL2422928 | 0.81 | AOC3 (0.58) | AOC3SIGMAR1ALOX5CHRM2HTR1A | |
| SCHEMBL8863944 | 0.77 | MLYCD (0.60) | AOC3SIGMAR1KMT2AMEN1 | |
| SCHEMBL8507046 | 0.76 | ALOX5 (0.50) | AOC3SIGMAR1ALOX5KMT2A | |
| SCHEMBL8751616 | 0.76 | SIGMAR1 (0.61) | AOC3SIGMAR1ALOX5KMT2A | |
| SCHEMBL29178457 | 0.75 | AOC3 (0.56) | AOC3SIGMAR1ALOX5CHRM2HTR1A | |
| SCHEMBL2097870 | 0.75 | NPY5R (0.56) | AOC3ALOX5KMT2A | |
| SCHEMBL10687119 | 0.74 | NPC1 (0.53) | AOC3SIGMAR1ALOX5KMT2A | |
| SCHEMBL7985986 | 0.74 | MLYCD (0.54) | AOC3SIGMAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264030-A1 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | Incyte Corporation (US) | 2010-12-22 | — | — | EP | disclosed |