Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | CES1 | P23141 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463897 | 0.95 | FAAH (0.54) | MLYCDFAAHCES1SIGMAR1ALOX5 | |
| SCHEMBL13181406 | 0.90 | MLYCD (0.64) | MLYCDFAAHCES1TACR1AOC3 | |
| SCHEMBL2422928 | 0.81 | AOC3 (0.58) | AOC3SIGMAR1ALOX5 | |
| SCHEMBL11796587 | 0.81 | PTGIR (0.48) | — | |
| SCHEMBL2316926 | 0.80 | RIPK1 (0.65) | MLYCD | |
| SCHEMBL8863944 | 0.77 | MLYCD (0.60) | MLYCDAOC3SIGMAR1 | |
| SCHEMBL12393190 | 0.76 | CTSK (0.46) | MLYCDFAAHCES1 | |
| SCHEMBL8751616 | 0.76 | SIGMAR1 (0.61) | AOC3SIGMAR1ALOX5 | |
| SCHEMBL29178457 | 0.75 | AOC3 (0.56) | AOC3SIGMAR1ALOX5 | |
| SCHEMBL12169769 | 0.75 | AOC3 (0.51) | AOC3SIGMAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1223659-A | Fused imidazopyridine derivatives as antihyperlipidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |