Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753760 | 0.87 | ALDH1A1 (0.42) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL6633897 | 0.71 | MAPK14 (0.45) | ALDH1A1MAPT | |
| SCHEMBL2301987 | 0.71 | MAPT (0.38) | LMNAALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL16925396 | 0.69 | BRD4 (0.32) | AOC3KMT2AATM | |
| SCHEMBL16097786 | 0.68 | — | — | |
| SCHEMBL477477 | 0.67 | EPHX1 (0.48) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL21542545 | 0.67 | EPHX1 (0.48) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL21542539 | 0.67 | EPHX1 (0.48) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL754901 | 0.67 | ALDH1A1 (0.36) | ALDH1A1HPGDHTTNPSR1TP53 | |
| SCHEMBL597442 | 0.66 | IDO1 (0.46) | LMNASMN1; SMN2ALDH1A1AOC3ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-2266958-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2010-12-29 | — | — | EP | disclosed |