SCHEMBL753760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13015262	0.87	LMNA (0.37)	ALDH1A1HPGDLMNASMN1; SMN2USP2
	SCHEMBL754901	0.75	ALDH1A1 (0.36)	ALDH1A1HPGDHTTNPSR1KMT2A
	SCHEMBL16921551	0.75	THRA (0.38)	ALDH1A1KMT2AATMMEN1THRA
	SCHEMBL12611006	0.74	KMT2A (0.44)	ALDH1A1LMNAKMT2AMAPTPKM
	SCHEMBL477477	0.73	EPHX1 (0.48)	ALDH1A1HPGDLMNASMN1; SMN2USP2
	SCHEMBL21542545	0.73	EPHX1 (0.48)	ALDH1A1HPGDLMNASMN1; SMN2USP2
	SCHEMBL21542539	0.73	EPHX1 (0.48)	ALDH1A1HPGDLMNASMN1; SMN2USP2
	SCHEMBL8138770	0.72	BCL2L1 (0.48)	ALDH1A1HPGDSMN1; SMN2KMT2ANPC1
	SCHEMBL16925396	0.71	BRD4 (0.32)	KMT2AATM
	SCHEMBL754893	0.70	KMT2A (0.50)	ALDH1A1LMNAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.